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In this instance, the concentrations of doxorubicin required to induce a deleterious GSH response fall firmly outside of the therapeutic ranges of circulating doxorubicin reported 40
Long-term benefits studied include healthspan extension, disease prevention, metabolic optimization, and biological age reduction
doi: 10.1007/s00109-024-02437-5
Furthermore, the impairment of some androgenic key enzymes and those related to the activity of seminiferous epithelium, together with the decrease in testosterone levels, could suggest an impairment of gonadal function through the alteration of some cellular pathways typically associated with tobacco consumption (Figure 8)